Direct MSA download

Download a paired or unpaired A3M

Look up one UniProt protein and download its indexed GreenFold alignment directly, with no model-specific bundling. If you need an AF2/AF3/Boltz/OpenFold3/Protenix-ready input instead, use a model page.

Step 1

Find a protein

Enter a UniProt accession, gene symbol, or entry name.

Step 2 · optional

Download from the command line or a script

This is the same endpoint the buttons above call: GET /v1/download_a3m/{uniprot}?kind=paired|unpaired. Full CLI guide.

curl

Python (requests)

Add &target=openfold to the URL to normalize paired-A3M headers for OpenFold3 — this does not change unpaired A3M.